Dorothy Tzu-Chen Yen, MD, PhD, is Professor and Director at the Department of Nuclear Medicine and the Center for Advanced Molecular Imaging and Translation, Chang Gung University and Chang Gung Memorial Hospital, Linkou, Taiwan. Dorothy Yen received her MD degree and PhD in Molecular Biology in 1982 and 1991, both from the National Yang-Ming University, Taiwan. Over the last two decades, her research interests felt into two broad categories: molecular and epidemiological aspects of malignancies in betel quid chewing endemic areas and neurodegenerative diseases. Her work focusing on head and neck malignancies and cervical cancer has been referenced by the Centers for Medicare and Medicaid Services (CMS) in the United States. Moreover, her research in the field of head and neck tumors has led to refinements of the AJCC guidelines (seventh and eighth editions, 2017 and 2018) and NCCN treatment guidelines (2016). In the field of neurodegenerative disease, Dorothy Yen has made significant contributions to the development of a cutting edge translational imaging platform in Taiwan (2004). She also advises leading pharmaceutical and healthcare companies (Eli Lilly, Biogen, Novartis, GE, and Siemens) in drug discovery and in the quest for new tracers for PET imaging of beta-amyloid, tau, and microglia.